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Discussion In contrast to the well-understood mechanisms for the function of soluble steroid reductases, for which numerous structures have been reported 48 , the molecular mechanisms governing the function of eukaryotic membrane-embedded steroid reductases have remained enigmatic due to limited structural information

In the autograft group, although the arrangement of sciatic nerve fibers in proximal parts was disrupted, this nerve was intact in the middle and distal parts (Fig

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Pharmacology of OR has been described with the message/address model: the ligand is composed of two parts, one carrying the activity (agonist or antagonist) at the different subtypes of OR, the message and one part, the address, conveying selectivity toward a given OR (Portoghese et al., 1990)