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Notably, although both CCKRs adopt the canonical seven-transmembrane architecture, they differ from other reported class-A GPCRs with a shortened TM4 helix, which is attributed to the unwinding of the helix at the extracellular half caused by the presence of P 4.59 and the additional P 4.61 (the superscripts refer to the BallesterosWeinstein number) 44

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Sterile water has no preservative, so once the vial is punctured, bacteria can grow

Lung tumor histology Histological analysis was carried out on all lung tumors in accordance with established protocols [57]