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Cigarette smoke was also shown to induce up-regulation of MHC class II, CD86 (B7-2), PDL2 and down-regulation of Inducible T-Cell Costimulator Ligand (ICOSL) on airway DCs
The overall picture of cancer risk is enormously complex and nuanced, so its important to keep in mind that this new study is subject to a number of assumptions
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