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It also is unknown whether the increases in standard smoking machine yields of these compounds have any biological relevance

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While this approach provides a good initial evaluation of the risk reduction potential of a cMRTP, it should be complemented with studies conducted in living systems (such as those described above) to further strengthen the evidence regarding the lung cancer risk reduction potential of a cMRTP

Forests are cleared for tobacco plantations and wood is burned to cure tobacco the drying of the tobacco leaf