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Both enzymes are ~25% identical to DPP-4 at the amino acid level
Under fiber-deficient diet, mucus-degrading bacteria expand and impair the integrity of the mucus layer
Across the evidence base, individual risk of bias is lowest overall among randomized human trials, moderate among observational studies, and inherently high among preclinical models and narrative reviews due to indirectness, despite strong mechanistic consistency
Depression in adults: recognition and management [NICE CG90]
