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How much of my personal Big Bang of Behavior Change was sparked by the GLP-1
Timeline varies based on starting weight, metabolism, and whether your body's peptide pathways are optimally matched to your specific GLP-1 medication
50,54 The weight loss appears to be sustained for up to 102 weeks

In this study, participants using semaglutide had a lower risk for CVD-related events when compared with placebo.38 These results build on prior evidence that GLP-1s not only support blood sugar and weight management but also offer significant cardiovascular protection in high-risk populations.39 A 2021 systematic review published in Diabetes & Metabolic Syndrome: Clinical Research & Reviews examined six studies involving over 182,000 adults with T2DM to evaluate the cardioprotective effects of GLP-1s (primarily liraglutide and exenatide) taken in conjunction with blood pressure and cholesterol lowering medications.40 The findings showed consistent improvements in cardiac function, including increased left ventricular ejection fraction40 and reduced heart chamber volume, along with weight loss and improved myocardial blood flow