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A clinical trial of sitagliptin in a small sample of patients with impaired glucose tolerance and mild T2DM found significant reductions in carotid intimal thickness in sitagliptin compared with diet control alone [122]

[DOI] [PubMed] [Google Scholar] 188.Giuse N.B., Koonce T.Y., Kusnoor S.V., Prather A.A., Gottlieb L.M., Huang L.C., Phillips S.E., Shyr Y., Adler N.E., Stead W.W
In contrast to dieting alone, these medications target underlying neuroendocrine mechanisms

Kucukali, I
