Tirzepatide in the Philippines
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The administration of semaglutide to HFpEF models resulted in an increase in cardiac ATP production that led to an improvement in heart contractility [11]
doi: 10.1177/1479164115605000 [DOI] [PubMed] [Google Scholar] 41
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Nevertheless, these findings point to complex interaction between GLP-1 and the gut, brain, immune system, and gut microbiota in control of inflammation (Figure 3 and Figure 4), offering osteoarthritis as a relevant inflammation model to explore the systemic, integrative actions of GLP-1 medicines beyond metabolic control (Figure 4)
