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135 It is noteworthy that MASLD patients exhibit diverse clinical characteristics, including biochemical markers, histology, and clinical outcomes due to varying body types, 136,137 which can lead to different treatment benefits

[7] Slowing down digestion One of the ways these medications work is by significantly slowing down the rate at which food leaves your stomach, helping you stay fuller for longer

This was speculated to result from increased calcium/calmodulin-dependent protein kinase I (CaMKI)/CREB levels and induction of calcium/calmodulin-dependent protein kinase kinase- (CaMKK)/AMPK signalling [131]

1, liraglutide, semaglutide and tirzepatide modulate shared risk factors for obesity and CKD, as they promote satiety, thus decreasing food intake, with all its components (e.g