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The quality of evidence was determined based on publication bias, indirectness, imprecision, inconsistency, and risk of bias

The website explicitly uses compounded GLP-1 products (not FDA approved), with the disclaimer buried in legalese and clear acknowledgment that these are not branded or FDA-validated versions of Ozempic, Wegovy or any other GLP-1s

The side effect profiles differ slightly between the two medications

Mass spectrometry verification Molecular weight confirmation: Mass spectrometry provides molecular weight measurement confirming compound identity
