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Diabetologia 39 , 12271232 (1996)
doi: 10.1016/j.ejphar.2008.03.025 172 GenglerSMcCleanPLMcCurtinRGaultVAHolscherC
Importantly, both the stalk and ECL1 of GCGR contain several -branched residues that favor the over conformation, in contrast to only one -branched residue (T207) in ECL1 and none in the stalk region in GLP-1R
In a similar patient population of adults with obesity who did not have diabetes, no severe or blood glucose-confirmed symptomatic hypoglycemic events were reported with semaglutide 1.0 mg [26]
