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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Iepsen EW, Lundgren J, Dirksen C, et al
In June 2025, the European Medicines Agency officially recognized NAION as a very rare side effect of semaglutide after reviewing all data, concluding it may affect up to 1 in 10,000 people and recommending product information updates
NICE recommends them when metformin and other therapies are insufficient, particularly for patients with high BMI, cardiovascular disease, or chronic kidney disease
Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing Metformin and/or sulfonylurea treatment in patients with type 2 diabetes
