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GLP-1R signaling has been investigated in a polygenic model of obesity using TALLYHO mice
Additionally, she said, the data did not account for residual confounders such as socioeconomic status, adherence and comorbidities

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But we must also consider possible long-term health benefits and cost savings as an important part of this equation, and the value of these drugs to patients health outcomes. Commercial insurance coverage for GLP-1 drugs is typically approved on a limited time basis, potentially several months to two years, and weight loss must be documented to maintain coverage, according to the commission
