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Allergy 65(1):6168 Zhao Q et al (2019) Clostridium butyricum alleviates intestinal low-grade inflammation in TNBS-induced irritable bowel syndrome in mice by regulating functional status of lamina propria dendritic cells

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Given a 95% confidence level (Z = 1.96) and a 5% margin of error (E = 0.05), and assuming a proportion (P) of 0.5 to maximize the required sample size, we calculated the necessary sample size using RaSoft sample size calculator (Raosoft, Inc., Seattle, WA, USA) [24] to be approximately 384