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The "up to 2 inches" is the maximum waist reduction seen, not the average the typical effect was more modest (around half an inch)

"We are not saying that semaglutide reverses aging or makes people younger," said the study's first author, Michael Corley, associate professor at UC San Diego School of Medicine and the Stein Institute for Research on Aging, in a press statement

It plays several critical roles in metabolic health, including: Promoting feelings of fullness and satiety Slowing gastric emptying (how quickly food leaves the stomach) Supporting healthy blood sugar and insulin response Reducing excessive appetite and food noise Aiding gut-brain signaling to help support better energy balance GLP-1 is released from the gut, so when you have a healthy gut, youre better able to release your own GLP-1 naturally

the clinician will advise alternatives