so glp-1 patches work are worse than you think (I was wrong) GLP-1 Patches: Do They Work?
Description
Some patients report feeling unusually cold during their first weeks of treatment, a symptom tied directly to decreased caloric intake and changes in thermogenic (heat-producing) pathways

doi: 10.4158/EP.15.6.540
In particular, women taking tirzepatide (Mounjaro), should also use condoms if they are on oral contraception and the weight loss medicines must not be taken during pregnancy, the regulator warned
But in the Retatrutide Phase 2 Obesity trial, Low Wang said that 100% of study volunteers who received 8 milligrams or more of the medication rather than the placebo lost at least 5% of their body weight