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The targets of area postrema neuronal projections include the rostral ventrolateral medulla (RVLM), with the efferent projections from the RVLM innervating the sympathetic preganglionic neurons (183)

Another limitation of the studies was the use of different comparators ranging from placebo controls to other medications for T2DM (including insulin), which have different effects on bone tissue and were included in only one group, misleading the interpretation

The molecular mechanisms underlying GLP-1 improvement of BP are incompletely understood

GLP-1 agonist drugs, which are synthetic versions of the naturally occurring GLP-1 hormone, have been used for decades in the treatment and management of Type II Diabetes Mellitus (T2DM)