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These findings are supported by a previous study, reporting a reduction in PASI, despite not being statistically significant, together with substantial improvement of BMI and cholesterol levels in an open-label trial of liraglutide in obese PsO patients (59)

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5.4 Comparison with other anti-obesity medications The latest generation of GLP-1 receptor agonists signifies a substantial therapeutic improvement compared to earlier alternatives

If we are willing to step beyond traditional abstinence-based paradigms, GLP-1RAs may pave the way for a more inclusive, effective, and pragmatic approach to reducing alcohol-related harm