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This inhibition consecutively leads to post-prandial GLP-1 plasma concentrations that are elevated 2-3-fold and mediates the glucose-dependent stimulation of insulin secretion and inhibition of glucagon secretion (10, 19)

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However, emerging research suggests that these drugs may come with an unexpected riskan increased incidence of ischemic optic neuropathy, a condition closely related to ischemic retinopathy