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In an exploratory posthoc analysis of the SURPASS-3 MRI substudy, results showed that patients treated with tirzepatide on top of metformin with/without an SGLT-2 inhibitor had a greater than predicted reduction of muscle fat

The TRIUMPH program spans four core trials covering general obesity, obesity plus knee osteoarthritis, obesity with cardiovascular disease, and obesity with type 2 diabetes, with nested protocols studying sleep apnea (OSA) within those same participant groups

D., Clemmensen C., Finan B., Dimarchi R

Le gnticien molculaire Jeffrey Friedman dcouvre en 1994 que les souris obses ont un gne dfectueux qui code pour la leptine, une hormone digestive peptidique qui induit une sensation de satit