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In fact, bile acids interact with gut microbiota by direct effects on the mucosal defense, membrane integrity, oxidative and pH stress to increase the growth of bile acid-metabolizing bacteria (183)
Clinical evidence suggests that weight management has a significant improvement on blood glucose control, insulin resistance, and beta-cell function in patients with T2DM [7,8]
Other regions Japan (PMDA): Typically 1-2 years after FDA approval
