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The mechanisms that drive enteroendocrine release of these gut peptides into the blood stream are multifactorial and include responses to direct nutrient stimulation, intracellular metabolism, or neuroendocrine mechanisms [see Psichas, et al
[Google Scholar] 6.Min T, Bain SC The role of tirzepatide, dual GIP and GLP-1 receptor agonist, in the management of type 2 diabetes: the SURPASS Clinical Trials
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But individual experiences vary
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