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The GLP-1 component activates hepatic AMPK/SIRT1 pathways, which inhibit SREBP-1c, a master regulator of de novo lipogenesis, thereby reducing hepatic triglyceride synthesis (37, 38)
[DOI] [PubMed] [Google Scholar] 260.Ritsner M, Maayan R, Gibel A, Strous RD, Modai I, Weizman A
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Understanding these trials, what they measure, and what the results mean, is essential for anyone tracking this compound
