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Figure 1 provides an overview of the mechanisms through which GLP-1 agonists help prevent stroke
W.PerkinsC.Jones-LeoneA.YangF.PerryC.et al (2016)
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Clinical studies reported slowed brain atrophy rates and stabilization of cognitive decline in monotherapy subgroups [82], but phase III outcomes were variable, and higher doses caused tolerability issues such as gastrointestinal, urinary adverse effects, and severe toxicity [27, 41, 61, 68]
