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Circulation, 149(17), e1298e1316
Results: GLP-1 RAs demonstrate pleiotropic effects through fundamental cellular mechanisms, including enhanced mitochondrial function, anti-inflammatory actions, improved cellular quality control, and comprehensive metabolic regulation
A claims-based database study indicated that the rate of discontinuation of GLP-1RAs in older individuals was high
However, semaglutide slows gastric emptying, which could theoretically affect the absorption timing of oral anticoagulants
