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Also, due to the important role of endothelial dysfunction in CVD, the effects of GLP-1RA on flow-mediated vasodilation (FMD) in patients remain to be investigated for their contribution to the CVD actions of GLP-1RAs
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Rare but serious side effects include pancreatitis (severe abdominal pain), gallbladder problems (upper right abdominal pain after eating), or thyroid concernsespecially in patients with a personal or family history of medullary thyroid cancer
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