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Description
EMPA-REG OUTCOME (Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients) was the first major trial published evaluating SGLT2-i use for reduction of MACE in patients with type 2 diabetes and known CVD on empagliflozin
One study warns that these drugs produce unsustainable volumes of toxic waste and non-degradable solid supports ( [20] ), prompting CDMOs to pursue greener chemistries and solvent-recovery systems (for example, water-based or continuous SPPS) as part of future-capex planning ( [21] ) ( [20] )
The length of treatment time should be around 6 months
doi: 10.1016/S0140-6736(14)60976-4 [DOI] [PubMed] [Google Scholar] 92.Sorli C, Harashima SI, Tsoukas GM, et al
