novo nordisk cuts prices for its glp-1 drugs. WEIGHT-LOSS DRUG ON THE DECLINE! This downward trend isn’t limited to a single medication. As competition increases and more treatment options enter the market, the overall cost of medically Novo Nordisk cuts Wegovy and

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Mei J, Sun J, Wu J, Zheng X

Try not to eat fast

Whats more, a recent retrospective, multicenter cohort study denied higher occurrence of nonarteritic anterior ischemic optic neuropathy (NAION) in GLP-1RAs users and suggested that its potential benefits for blood glucose control and cardiovascular health likely outweigh its risks (Chou et al., 2025), despite that a few research have reported association between semaglutide prescription and a higher risk of NAION(61)

In the meantime, mitochondrial dysfunction is induced by hepatic IR and lipid accumulation and the lipid peroxidation mediated by cytochrome p450 2E1 boost the production of reactive oxygen and promote the degradation of mitochondria (125), which could further lead to the lack of cellular energy and metabolic intermediates accumulation, all these may lead to the secretion of pro-inflammatory cytokines, hepatocellular apoptosis and hepatic fibrogenesis, finally resulting in cirrhosis of the liver (125) ( Figure 3 )