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The ADA now recommends GLP1 RAs with proven benefit to slow CKD progression and reduce CV risk in people with type 2 diabetes
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GLP-1GIPlanifibranor, a single-molecule agonist of GLP-1R, GIPR, PPAR, PPAR and PPAR, shows promising therapeutic efficacy against obesity-linked metabolic dysfunction in vitro and in mouse models via synergistic incretin and PPAR activity.
