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The key safety consideration involves baseline health status: men with active prostate cancer, severe liver disease, or uncontrolled hypertension require individualized risk assessment before starting GLP-1 therapy alongside TRT

suspectum venom that have received the most attention from researchers are the bioactive peptides, including helodermin, helospectin, exendin-3, and exendin-4

This GLP-R1 agonist seems to increase oncogenesis in multiple tissues, including the thyroid, bladder, pancreatic, and colorectal [97, 110, 121]

Causes and Risk Factors Behind Reduced GLP-1 Response Although reduced responsiveness to GLP-1 therapy is still being studied, several contributing factors have been identified