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Theyre not going to have the same effects as drugs such as Ozempic, which stay in the body at a lot higher levels. Notably, semaglutide drugswhich mimic GLP-1bind to GLP-1 receptors and activate them but have a much longer duration of action due to their structural modifications, which make them less susceptible to enzymatic degradation, he points out
The functional implication of this unique spatio-temporal trafficking and signaling is yet unclear
