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Keywords GLP-1 Agonists SGLT-2 Inhibitors Diabetes Mellitus Chronic Kidney Disease Liver Transplantation Introduction Despite the life-saving intervention of liver transplantation for patients with ESLD (end-stage liver disease), the success of transplantation is compromised often by post-transplant complications, particularly diabetes mellitus and chronic kidney disease (CKD)

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More recently, the concept of nutrient-stimulated hormone-based therapeutics, involving novel combinations like GLP-1 with other gut hormones such as GIP and glucagon, highlights the growing importance and effectiveness of GLP-1 based therapies in managing these chronic conditions