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First, we observed an increased number of activated PSCs in L-arginine-induced AP, which is consistent with findings from a previous report, 63, 64 which demonstrated increased -SMA expression (a marker for activated PSCs) coincided with TGF- 1 activation in this model
Though preliminary, these findings offer a potential new tool for managing the obesity-related risks in breast cancer.
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These factors often work together in ways that aren't immediately obvious, making it difficult to pinpoint what needs adjustment
