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Relative to STRs (T1R2/T1R3) and umami taste receptors (T1R1/T1R3), the biology of BTRs (T2Rs) appears to be more complex due to their diversity

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The intracellular [Ca 2+ ] rise triggered by glycine (monitored as the 340/380 nm fluorescence ratio in fura-2-loaded cells) was inhibited by both strychnine (10 m) and picrotoxin (100 m), whereas the response to GABA was abolished by picrotoxin but only marginally impaired by strychnine (Fig

At 0.4 g/ml, 20 min of prior exposure to oligomycin was needed to achieve significant reductions