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At present, our best recent science suggests that underlying genetic factors moderate our response to GLP-1 medicines

Thats the implication of a new study that examined health records of people with type 2 diabetes and opioid use disorder
Additionally, sleep disturbances also disrupt the production of hunger hormones like leptin, ghrelin, and insulin

Since fiber helps with regularity, it can also help minimize constipation, a common side effect on GLP-1s like Wegovy