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Your provider may recommend imaging studies, gastric-emptying tests, or referral to a gastroenterologist if gastroparesis is suspected

Since one of us (S.P.) frequently prescribes GLP-1 receptor agonists for metabolic dysfunction-associated fatty liver disease (MAFLD) patients with obesity, a review of some pearls may be helpful

But unlike natural GLP-1, which decays very rapidly (its half-life is just 2 minutes), synthetic GLP-1 receptor agonists are long-acting and remain active in your body for hours or days

Tirzepatide activates GLP-1 and GIP receptors simultaneously, engaging dual-pathway activation that can overcome single-pathway desensitization