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Nielsen et al

However, it is noteworthy that a 26-week treatment of dulaglutide 1.5 mg or tirzepatide 5 mg showed comparable outcomes in improvements of MASH and liver fibrosis biomarkers, including liver enzymes, keratin-18, procollagen III, and adiponectin

These observations reinforce the broader principle that the impact of preventive therapies is often greatest in high-risk populations, aligning with the risk-based treatment paradigm increasingly endorsed by contemporary clinical guidelines
