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In animal models of HF, GLP-1R agonists increase myocardial glucose uptake [62], stroke volume and LVEF, accompanied by decreasing LVEDP and systemic vascular resistance [63]

Victoza and Rybelsus.are taken once per day (Victoza is a once-daily injection while Rybelsus is a once-daily pill.) The price of GLP-1 agonists tends to be higher compared with most other medicines for treating type 2 diabetes
