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doi: 10.1126/scitranslmed.3009759 [DOI] [PMC free article] [PubMed] [Google Scholar] 114.Frohlich EE, Farzi A, Mayerhofer R, et al

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Clinical trials show that patients typically regain significant weight after discontinuation

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Possible concerns may include nausea, vomiting, diarrhea, constipation, appetite suppression, dehydration, fatigue, gallbladder concerns, blood sugar changes, excessive weight loss, and loss of lean muscle if weight drops too quickly

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