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doi: 10.1126/scitranslmed.3009759 [DOI] [PMC free article] [PubMed] [Google Scholar] 114.Frohlich EE, Farzi A, Mayerhofer R, et al

Clinical trials show that patients typically regain significant weight after discontinuation

Possible concerns may include nausea, vomiting, diarrhea, constipation, appetite suppression, dehydration, fatigue, gallbladder concerns, blood sugar changes, excessive weight loss, and loss of lean muscle if weight drops too quickly

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