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Specifically, MDL29,951 stimulated calcium flux with 220 nM potency (pEC 50 = 6.660.13) and maximum peak F/F of 0.800.07 in cells expressing hGPR17L, whereas the peak F/F in response to 30 M MDL29,951 treatment was 0.010.01 in control-transduced cells (Figure 1B)

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Drawing from peer-reviewed research, federal guidance, and public health literature, the poster highlights high-evidence strategies such as naloxone distribution, low-threshold access to medications for opioid use disorder, syringe services programs, and community-based drug checking

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