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Or, more specifically, an insatiable need for it

Importantly, the levels of these neurotransmitters can be different according to the phase of BD (Fig

More recently, it has received approval for use as an anti-obesity medication, marketed under the brand name Wegovy

acts centrally to reduce appetite Setmelanotide : Reserved for specific genetic obesity syndromes (e.g., POMC/PCSK1/LEPR deficiency, Bardet-Biedl syndrome) under specialist supervision Non-pharmacological interventions form the cornerstone of weight management and may be particularly appropriate: Structured lifestyle programmes : NICE recommends multicomponent interventions including dietary modification, increased physical activity, and behavioural strategies