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Nersessian et al

Domino's Pizza CEO Russell Weiner sounded unshaken when he told analysts last month that the pizza chain hasn't seen GLP-1 drugs affect its sales yet

Contrave targets appetite and reward pathways in the brain to reduce cravings and improve impulse control around eating
So if you are feeling a sense of urgency or firmly want to get started, the risk of delaying other effective treatments (see below) until the duration of the study is completed may not be worth it
