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The practical advice outlined in this article should help GPs to prescribe GLP-1RAs safely and effectively and ensure patients benefit from these new potent and multifaceted agents

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Knowledge of the hypothalamus has only recently evolved from anatomical concepts (nuclei, areas and fibre tracts) to neurochemicals (characterizing the distributions of neuropeptides and transmitters and their receptors), focusing on the modulation of feeding behaviour and energy expenditure

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The acetazolamide monotherapy group was compared with the combined therapy group

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