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According to the group of authors, these polyagonists are in all likelihood the next step towards a cure for diabetes and obesity. Comparable to bariatric surgery The authors report on various polyagonists that are currently being researched in clinical studies and show improved efficacy with each new generation. The latest triple agonists attack both the glucose-dependent insulinotropic peptide receptor (GIPR) and the receptors for glucagon-like peptide 1 (GLP1) and glucagon (GCG, a hormone from the pancreas)

Researchers using the peptide calculator should factor this pharmacokinetic reality into their planning

Cai, M., Xie, Y., Topol, E

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