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An extensive list of agents including thiazolidinediones, insulin-like growth factors, fibroblast growth factors, gastrin, glycogen synthase kinase-3 (GSK-3) inhibitors, protein kinase dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitors, gamma-aminobutyric acid, quinolones, sphingosine phosphate, oestrogens and phytoestrogens, polyphenols, flavonoids and other plant compounds has been reported to increase beta cell proliferation in vitro or in animal models, but specifically targeting these agents to pancreatic beta cells in vivo remains an unfulfilled therapeutic challenge [30]

Most providers prescribe only to adults, with age and health screenings determining eligibility

Kim SR, Chen X, Oo TF, Kareva T, Yarygina O, Wang C, et al

Many have searched high and low for affordable options and treatments to help manage what the medical community knows is a disease