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348 While it is well known that FOXA1 is very difficult to target, the proteolysis targeting chimeras (PROTACs), such as oligonucleotide-based PROTACs (OPROTACs), 575 present a new opportunity to develop novel anticancer agents targeting FOXA1 and its mutations

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Bianchi L, Marash SAB, Malatesta N, et al