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[5] Some patients with obesity may have mild elevations in cortisol or altered cortisol metabolism related to their weight status, and substantial weight loss could potentially normalise these patterns, though evidence for this specific effect is limited

Cancer development is often a slow process, and longer-term surveillance data will be valuable as patients continue these medications for extended periods, particularly for weight management in younger populations without diabetes

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While this is excellent news for those who struggle with their weight, there are some disadvantages to consider