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The glucose-dependent insulin secretion mechanism of GLP-1R and GIPR agonism means that insulin release is amplified only when blood glucose is elevated, reducing the risk of hypoglycaemia compared to insulin or sulfonylurea-based interventions
What the 2025 Expert Consensus Found Using a Delphi process with 58 experts from 17 countries, the panel reviewed available evidence and reached key agreements: 1

2019;5: e02275
