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Promisingly, because GLP-1 medications promote weight loss and, therefore, reduce fat tissue, they might help downregulate pro-inflammatory molecules

A systematic review and meta-analysis published in eClinicalMedicine reported pooled mean weight regain of 5.63 kg and 5.81 percent of body weight

Post-cholecystectomy patients often experience continuous bile flow, which can amplify GLP-1 side effects such as nausea and diarrhea
Both these effects contribute to weight loss during GLP-1 RA therapy and consequently to a decrease of the inflammatory burden thanks to the decline in adiponectin [6, 32]
