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GLP-1: Limited Driven by chronic low-grade inflammation that disrupts fat storage regulation, insulin sensitivity, and leptin response

Their experience highlights patient safety concerns around compounded GLP-1 drugs: inconsistent quality control, unclear sourcing, potential contamination, dosing errors, and delayed recognition of serious adverse effects

Retevmo is specifically indicated for advanced or metastatic medullary thyroid cancer with a RET mutation, advanced or metastatic thyroid cancer with a RET gene fusion untreatable with radioactive iodine therapy, and locally advanced or metastatic solid tumors with a RET gene fusion that have progressed after prior systemic treatment or have no treatment options, according to the publication

These require medical evaluation and may necessitate temporary dose reduction or discontinuation pending resolution